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As for fatigue, resting when needed and ensuring balanced meals to maintain energy levels may help reduce this symptom

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Weight loss also tends to follow a dose-response pattern, meaning higher doses generally produce greater average reductions in body fat

Always consult your healthcare provider if your symptoms worsen or fail to improve or if you have any other concerns about your treatment

This likely reflects the cumulative nature of eGFR slope as a measure of decline over time, where small annual differences may not translate into substantial absolute separation over shorter follow-up intervals