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While Mounjaro commonly causes gastrointestinal side effects like nausea and diarrhoea, there is limited evidence that these are significantly worse in post-cholecystectomy patients

Do Not Use Mounjaro If You Have A personal or family history of medullary thyroid carcinoma Multiple Endocrine Neoplasia syndrome type 2 A serious allergic reaction to tirzepatide or any ingredient in Mounjaro Warnings and Precautions Mounjaro shares the same safety profile as Zepbound including warnings about pancreatitis, hypoglycemia (particularly with insulin or sulfonylureas), gallbladder disease, acute kidney injury, hypersensitivity reactions, severe GI disease, hormonal contraceptive interactions, diabetic retinopathy complications, and delayed gastric emptying increasing aspiration risk during anesthesia

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Semaglutide also helps patients lose weight an important secondary benefit that further improves blood sugar management and cardiovascular health