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We therefore used metformin as a control group in an analysis including 288,675 patients with NAFLD and type 2 diabetes, of which 103,667 individuals were receiving metformin (metformin group

thus, inhibiting GR sensitises cells to oxidative stress [31]

GLP-1 and GIP receptors can form dimers, which then increases the amount of cAMP produced and, furthermore, can change the second messenger cascade to a PLC-IP3-PiP3-Alt/PKB cascade [103, 104] (Fig