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In preclinical models and early human data, it has been hypothesised that the additional glucagon receptor activity may contribute to increased energy expenditure and broader metabolic effects

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The condition is characterised by transmural inflammation meaning it affects the full thickness of the bowel wallwhich can lead to complications including strictures, fistulas, and abscesses

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For instance, Dysport requires more units per injection to equal Botox or Xeomin, i.e