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Boody weight was reduced by 6.0 kg after 24 months and 5.8 kg after 36 months

As of 2025, there are no FDA-approved generic versions of semaglutide available in the United States

GLP-1 agonists work by mimicking the incretin hormone GLP-1 , which enhances insulin secretion, suppresses glucagon release, slows gastric emptying, and reduces appetite

Oral delivery of peptides faces inherent challenges due to enzymatic degradation in the gastrointestinal tract, and sublingual absorption offers a partial workaround by allowing the peptide to enter the bloodstream through the mucous membranes under the tongue