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Characterizing crosstalk in epigenetic signaling to understand disease physiology

Clinically, GLP-1s show potential beyond diabetes and obesitythere's promise in areas like sleep apnea and cardiovascular conditions, he explained

(NCBI) Think of GLP-1 signalling as an appetite brake + pacing system: Brain: appetite and reward modulation Gut: slower gastric emptying Pancreas: insulin secretion (glucose-dependent) and reduced glucagon secretion (context-dependent) The critical factor is that the lack of appetite typically leads to a caloric deficit