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The official antioxidants definition is any substance that inhibits oxidation, which helps prevent free radical formation and protect against disease

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Inhibition of KEAP1 by RTA 408 disinhibits the antioxidant transcription factor nrf2 and has neuroprotective and seizure reducing effects in the kainic model of TLE (Shekh-Ahmad et al., 2018)

Expanding or painful redness warrants stopping and contacting a clinician