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Notable Studies: Efficacy and safety of liraglutide 3.0 mg in patients with overweight and obese with or without diabetes: a systematic review and meta-analysis Efficacy and safety of liraglutide for obesity and people who are overweight: a systematic review and meta-analysis of randomized controlled trials The effectiveness and safety of liraglutide in treating overweight/obese patients with polycystic ovary syndrome: a meta-analysis Also Known As: Victoza, Saxenda, Xultophy, NN2211, GTPL1133 Research Applications: Weight loss Metabolic syndrome PCOS Neuroprotection Risks: Nausea and gastrointestinal upset Injection site reactions Tachycardia Potentially pancreatitis and neoplasias FDA approval limited to T2D and overweight/obese patients Chemical Structure What is Liraglutide

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Expectedly, GPR120 agonism shows powerful anti-diabetic, anorexic, and hepatoprotective properties in multiple animal models (275, 284287), at least partially mediated by GLP-1 (288)

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