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Nature Scientific Reports

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An in vitro study using human hepatocytes showed that catecholamines, such as adrenaline and noradrenaline, mimic the action of lipopolysaccharide (LPS), with activated -AR leading to excessive secretion of interleukin-6 (IL-6), thereby exacerbating inflammation and inhibiting CYP3A4 expression

REM) in longitudinal studies and increased significantly in cross sectional studies (2.58 [1.68, 3.53]

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