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doi: 10.1177/0884533611436116 69 LiX.ChuL.LiuS.ZhangW.LinL.ZhengG

Results: We identified three novel homozygous loss-of-function mutations (c.2927_2928delCT, p.(Pro976Argfs*42)

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When we demand that New Approach Methodologies demonstrate "equivalent or better" performance, we must benchmark them against what animal studies actually deliver, not what we assume they deliver