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In the SCALE Obesity and Prediabetes trial (N=3,731), participants receiving liraglutide 3.0 mg daily lost a mean of 8.0% of body weight over 56 weeks, compared with 2.6% in the placebo group [1]

The GLP-1 agonist era beginning with liraglutide (Saxenda) marked a paradigm shift toward medications that worked with the bodys natural appetite regulation systems rather than against them

doi:10.1016/j.amjmed.2025.01.021 Meloni AR, DeYoung MB, Lowe C, Parkes DG

For employers and insurers, the initial question was whether to cover GLP-1s for obesity, said Virta CEO Sami Inkinen