doi: 10.1016/j.semcdb.2004.05.001
A good supplier lists every component and its exact quantity in plain view, while a vague label is a warning sign in itself
GSH is synthesized exclusively in the cytosol in two consecutive ATP-requiring steps, the first of which, and rate limiting, being -glutamylcysteine formation by glutamate-cysteine ligase (GCL)
You want to just knock the right pieces, but not upset the whole applecart
JACC Basic Transl Sci 9(8):10411052 Haghighi K, Kolokathis F, Gramolini AO, Waggoner JR, Pater L, Lynch RA, Fan GC, Tsiapras D, Parekh RR, Dorn GW 2nd, MacLennan DH, Kremastinos DT, Kranias EG (2006) A mutation in the human phospholamban gene, deleting arginine 14, results in lethal, hereditary cardiomyopathy