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Excess adipose tissue, particularly visceral fat, promotes systemic inflammation and insulin resistance while reducing testosterone levels through increased aromatase activity that converts testosterone to estrogen

Glucagon receptor activation may partially counter metabolic adaptation by maintaining higher energy expenditure despite reduced body mass

Hatta baz kadnlar iin GLP-1 tedavisi, hamile kalma olasln artrabilir

Melanocortin-4 receptor-regulated energy homeostasis

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