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IGF-1 LR3 (Long Arg3 IGF-1) is a recombinant analog with two structural changes relative to native IGF-1: A glutamic acid to arginine substitution at position 3, which reduces IGFBP binding affinity

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Ann N Y Acad Sci 1053:153161 Zaitone SA, Abo-Elmatty DM, Shaalan AA (2012) Acetyl-l-carnitine and alpha-lipoic acid affect rotenone-induced damage in nigral dopaminergic neurons of rat brain, implication for Parkinsons disease therapy

It is important to follow the manufacturer's recommendations and combine it with a balanced diet and physical activity