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Formulation R1 (3 mg, 7 mg, 14 mg) Weeks 1-4: 3 mg once daily (starting dose, not effective for blood sugar control) Weeks 5-8: 7 mg once daily Week 9 onward: Stay on 7 mg if effective, or increase to 14 mg once daily if more control is needed Formulation R2 (1.5 mg, 4 mg, 9 mg) Weeks 1-4: 1.5 mg once daily Weeks 5-8: 4 mg once daily Week 9 onward: Stay on 4 mg if effective, or increase to 9 mg once daily if more control is needed Who can use it

10.1016/j.jacbts.2018.09.004 50

B., Button, B., Rubinstein, M

Objectively Measured Physical Activity and Sedentary Behavior in Successful Weight Loss Maintainers

Human evidence is identified below as either from randomized controlled trials (RCT) or preliminary studies, which may or may not include an untreated control group