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10.1021/acs.jafc.6b02750 31 LaiR

Ferroptosis is an iron-dependent, lipid peroxidation-driven cell death process characterized by glutathione (GSH) depletion and inactivation of glutathione peroxidase 4 (GPX4), leading to the accumulation of lipid peroxidation products (e.g., MDA and LPO) and cell membrane rupture, hallmark features include mitochondrial alterations (e.g., reduced cristae and increased membrane density), elevated lipid peroxidation, and dysregulated iron metabolism (Jiang et al

Recipient Epidemiology and Donor Evaluation Study-III (REDS III)

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Bone marrow-derived myeloid cells transiently colonize the brain during postnatal development and interact with glutamatergic synapses