10.1002/tox.23031 Environ
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doi: 10.1016/j.intimp.2020.106206 149 DongMMengZKuerbanKQiFLiuJWeiYet al
Sh-Polypeptide 9, a VEGF-like biomimetic peptide, promoted endothelial tubulogenesis and VEGF production more effectively than minoxidil in an in vitro co-culture system of DPCs and microvascular endothelial cells [99]
It depends on both copper and zinc as cofactors, but only copper regulates its activity ( 2 O 2 , CuZn-SODs activity is suppressed, via oxidation of His-118 to form 2-oxo-histidine ( Cytochrome c oxidase, also known as complex IV, at a final step in the respiratory chain, catalyzes the reduction of oxygen to water
