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The FTO rs9939609 variant and MC4R rs17782313 polymorphismboth assessed in PlexusDx testingcorrelate with differential metabolic flexibility during weight loss

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Then, articles were scanned and the data from these studies was extracted, including the number of patients per arm, L-carnitine dosing (including initial loading dosing and daily oral maintenance dosing), acute MI (AMI) index event type, follow-up duration, and outcomes (i.e., all-cause mortality, adverse cardiovascular events including unstable angina, acute MI, heart failure, and ventricular arrythmia)