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These medications can help regulate appetite and promote weight loss if diet and exercise alone havent worked

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Last reviewed: June 19, 2026 Last updated: June 19, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

The same study found that people taking Wegovy were more likely than those in the placebo group to lose 5, 10, 15, or 20% of their starting weight

Some plans cover the medication for patients with BMI 30 or BMI 27 with weight-related comorbidities, but prior authorization requirements, step therapy protocols, and high copayments create significant barriers