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Our future studies will prioritize this therapeutic potential

For B12 deficiency treatment , the approach depends on severity, underlying cause, and presence of neurological symptoms

Similar findings were discovered in preclinical animal models of lung cancer (31) and melanoma (199), in which most tumor-specific CD8+ T cells in the TDLNs are functional and exhibit a gene expression signature resembling that of stem-like CD8+ T cells (31) or resident memory CD8+ T cells (199), suggesting that the antigen presentation and T cell priming in TDLNs is critical for the ICB treatment

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