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Ask specifically if the patient is taking any of the GLP-1 agonist medications
14 Wholegrain bread, rolled oats, brown rice, beans, nuts and seeds, lentils, vegetables, and fruit are the main sources
For patients who cannot tolerate statins or require additional lipid lowering despite maximum tolerated statin therapy, NICE guidance supports several alternative or adjunctive treatments: Ezetimibe : Reduces cholesterol absorption from the intestine and can be used alone or in combination with statins PCSK9 inhibitors (evolocumab, alirocumab): Injectable medications reserved for specific high-risk patients with familial hypercholesterolaemia or established cardiovascular disease who have not achieved targets with other therapies Bempedoic acid : A newer oral option for patients with statin intolerance Inclisiran : An injectable treatment given twice yearly for primary hypercholesterolaemia or mixed dyslipidaemia in line with NICE criteria Icosapent ethyl : For people with established cardiovascular disease and raised triglycerides despite statin therapy Fibrates : Primarily used for severe hypertriglyceridaemia Lifestyle modifications remain fundamental to cholesterol management and should be implemented alongside any pharmacological treatment
What changes is the added B12 support and, in some cases, the overall experience
