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In light of those potential long-term healthcare savings and the encouraging numbers weve seen on that front so far, however, assuming that demand doesnt spike in line with worst-case scenario forecasts over the next few years, the trend toward covering semaglutide and GLP-1 for weight loss purposes with some restrictions seems likely to pick up momentum barring unforeseen events

People who take the most common categories of weight-loss drugs, semaglutide and tirzepatide, marketed as Ozempic, Wegovy and Zepbound, tended to lose about 33 pounds during their treatment but then regained about 22 pounds in the first year after stopping, Sam West, a physiology researcher at Oxford University who co-wrote the study, said in a phone interview Thursday

The potential of GLP-1/glucagon dual receptor agonist on steatohepatitis, fibrosis and liver regeneration has also shown some promising results in clinical studies (55) and may have a therapeutic potential in NAFLD

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