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High levels of catecholamine metabolism in the midbrain are associated with increased levels of neuromelanin in the same region and, it is neuromelanin that is thought to be one of the molecules responsible for inducing chronic neuroinflammation in PD

Therefore, it is urgently needed to screen effective medicines and identify new therapeutic molecular targets

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Under dark conditions at 25 C, the absorbance of the nitro-2-thiobenzoate anion (TNB-) at 412 nm remained consistent for more than three hours

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