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doi: 10.3390/ijms21082861 50 LevringTBHansenAKNielsenBLKongsbakMvon EssenMRWoetmannAet al

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Neovascularization involves several growth factors and cytokines, such as fibroblast growth factor (FGF), platelet-derived endothelial cell growth factor (PD-ECGF), angiopoietin (Ang)1/2, matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9), among which vascular endothelial growth factor (VEGF) is the most vital irritant