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When activated, they slow down intestinal movement, delay stomach emptying, and alter the migrating motor complex

In the future, a multidimensional line of evidence is needed to clarify the source of GLP-1RA effects in IBD, including in vitro experiments to confirm direct actions, animal models designed to exclude metabolic interference, and clinical data adjusted for metabolic confounders

The decision to use these treatments should involve a comprehensive discussion of individual risk factors, family history, and the balance between metabolic benefits and potential concerns

(1993) GLP-1 stimulates secretion of macromolecules from airways and relaxes pulmonary artery

Glucagon-like peptide-1 acutely affects renal blood flow and urinary flow rate in spontaneously hypertensive rats despite significantly reduced renal expression of GLP-1 receptors