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Protective effects of honokiol against methylglyoxal-inducedosteoblast damage

When RPL15 is overexpressed, the number of nucleoli and the expression of nucleolar proteins increases, and the abnormal increase in nucleolar size and number caused by dysregulation of ribosome biosynthesis is a hallmark of most spontaneous cancers [47]

266 Additionally, liver-specific deletion of RNF43/ZNRF3 leads to increased levels of unsaturated lipids and the development of steatohepatitis, while also causing uncontrolled regenerative capacity following chronic damage, thereby increasing the risk of carcinogenesis

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