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Notably, the reductions observed in these parameters were greater than those seen with semaglutide 1 mg, another GLP-1 receptor agonist, in the SUPRASS-2 trial.Tirzepatide was generally well-tolerated, with a low risk of hypoglycaemia when used without insulin or insulin secretagogues

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This molecular mechanism of antimicrobial action, based on the physicochemical interaction of molecular charges and membrane insertion (Figure 1B), results in a wide spectrum of antimicrobial activity that covers Gram-positive G (+) and Gram-negative G () bacteria, as well as viruses and fungi (Hashemi et al., 2018