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A newer GLP-1 receptor agonist, tirzepatide, demonstrates weight loss as high as 20% change in body weight compared with 3% in the placebo group in a RCT
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GLP-1RAs regulate lipid metabolism and induce autophagy through AMPK/SIRT1 pathway to improve NAFLD
Withdrawal symptoms can also occur when individuals stop taking GLP-1 medications: Reduced side effects: While semaglutide or tirzepatide can lead to side effects like acid reflux, nausea, constipation and abdominal pain, stopping the medication can reduce these side effects
He is a founder of the American Board of Obesity Medicine (ABOM), past President of The Obesity Society (TOS), and past board member of the Obesity Action Coalition (OAC)
