India is home to over 100 million people with diabetes and approximately 250 million classified as obese or overweight.[15] What makes the situation uniquely dangerous is the Thin-Fat Indian paradox: South Asians tend to accumulate more visceral (belly) fat, liver fat, and less lean muscle mass at lower body weights than Western populations.[8][9][10] While GLP-1 medications are a global phenomenon, they are particularly critical for the Thin-Fat Indian phenotype
To reduce side effects Nausea, vomiting, constipation and fatigue are among the most common side effects of GLP-1 drugs, and how hard they hit can depend, at least in part, on the dose
Data on kidney outcomes remain limited, but SGLT2is appear particularly effective when kidney protection is the primary goal, regardless of concurrent treatment
Ideal body weight can be estimated using the following formulas: for females, start with 100 pounds for the first 5 feet of height and add 5 pounds for each additional inch
M., Pellegrino, M
