For individuals with alcohol use disorder specifically, additional safety considerations arise
When muscle is lost during weight management, it can result in: Decreased metabolic rate Reduced physical strength and endurance Difficulty maintaining weight loss long-term Diminished quality of life and functional capacity For those using medical weight management approaches, these concerns become even more pressing, as the accelerated weight loss can sometimes lead to greater muscle breakdown without proper nutritional support
As research continues to elucidate additional mechanisms and clinical applications, the therapeutic scope of GLP-1RAs is expected to further diversify.[21] This review summarizes emerging and established evidence on the use of GLP-1RAs beyond glycemic control in diabetes, highlighting current indications, investigational uses, and future directions for this evolving class of agents
MacDonald PE, El-Kholy W, Riedel MJ, et al
BBR has proven to promote insulin secretion, enhance insulin sensitivity, inhibit gluconeogenesis, reduce fat accumulation, avert steatosis and fibrosis, display anti-inflammatory and antioxidant properties, and modulate the immune system in both animal and human studies [5]
