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In vitro studies on aged human lymphocytes found that Epitalon reversed this heterochromatinization, increasing chromatin plasticity and making DNA more accessible to transcription factors

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Front Aging Neurosci 13:649929 Jung S, Kim K (2014) Exercise-induced PGC-1 transcriptional factors in skeletal muscle

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Some studies note nausea and gastrointestinal upset but did not feel it was related to the supplementation, says Manning