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The topical route is the format with the strongest human clinical trial evidence for skin outcomes, from the landmark 1998 Abdulghani study that outperformed both vitamin C and tretinoin to the Finkley skin-thickness data

The strongest human clinical evidence is for topical use, including the Leyden 2002 photoaging trial and a 2023 NEEL gel topical study reporting an average 28% increase in skin collagen density at 3 months

Liraglutide: a once-daily incretin mimetic for the treatment of type 2 diabetes mellitus

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This combination is especially valuable for the ones recovering from injuries, handling with continual health conditions, or simply aiming to maintain optimal health