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High Cortisol Levels: Cortisol, the stress hormone, can increase your appetite and signal your body to store fat, particularly if youre under chronic stress

Wegovys standard maintenance dose is 2.4mg, and the 7.2mg step-up dose (MHRA approved January 2026) produces 20.7% average weight loss

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Most people start with 2mg weekly and gradually increase to 4mg, then 8mg, and potentially up to 12mg as the maximum dose

Most guidance points to stopping GLP-1 medications at least two months before you actively try to conceive, since these drugs can linger in your system for weeks (University Hospitals)