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Results Semaglutide lowers blood glucose and improves glucose tolerance in obese mice similar to calorie restriction In high-fat diet-induced mice, treatment with semaglutide or calorie restriction for 4 weeks substantially reduced body weight (Fig

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[PubMed] [PMC] Estato V, Obadia N, Chateaubriand PH, Figueiredo V, Curty M, Costa Silva M, Ferreira RGL, Santa-Ritta J, Campos Baroni M, Arago A, Neno JOG, Vasconcellos CAM, Costa DAvila J, Gomes Granja M, Caire De Castro Faria-Neto H (2025) Semaglutide restores astrocyte-vascular interactions and blood-brain barrier integrity in a model of diet-induced metabolic syndrome

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Analysis of NMDA-evoked CBF changes included assessing the peak amplitude, time to peak, and area under the curve (AUC), with the AUC calculated from the onset of stimulation to 100 sec post-stimulation

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