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On enterocytes and monocytes, gliadin binds to the CXCR3 chemokine receptor, which provides a signal for the cell to increase zonulin synthesis

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I administer B12 injections subcutaneously, which means right under the skin and not into the muscle

"The effects of collagen peptide supplementation on body composition, collagen synthesis, and recovery." Amino Acids , 53, 14931506

Also, some peopl have an autoimmune or inflammatory condition of the stomach wall that degrade the proteins that aid vitamin B12 absorption