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In summary: Survodutide (BI 456906) is an investigational GCGR/GLP-1 dual agonist being developed globally by Boehringer Ingelheim (under license from Zealand Pharma), now in Phase 3 for obesity with compelling Phase 2 weight-loss data that support its differentiation from existing GLP-1 therapies and strong potential across cardiometabolic indications

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This difference is explained further in the comparison of IV therapy vs oral supplements

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Studies in the field of accelerated aging have established a link between PARP activation and impaired mitochondrial health, which is associated with reduced NAD + levels resulting from PARP hyperactivation 158