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Bioactivation of nephrotoxic cysteine S-conjugates in mitochondrial outer membrane

The plasma concentrations of the GLP-1 WT albiglutide-mimic and Tanzeum were comparable at the following time points, resulting in similar PK properties (Supplementary Fig

The observation that liraglutide is taken up in a GLP-1Rdependent manner and directly binds to neurons within the ARC and other CNS regions raises questions about the central mechanisms of action and the efficacy of larger nonpeptide GLP-1R agonists

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The change in the firing rate of IPN can also explain the impaired performance in the eyeblink response of Lurcher mice compared to WT mice [201]