When in doubt, starting fresh with new reconstitution or a new vial is safer than continuing with potentially degraded peptide
The STAT News coverage noted that if the FDA ultimately reclassifies the compounds and they are produced by compounding pharmacies, clinicians would have discretion to prescribe them outside the narrow indications under review, meaning a substance reviewed only for ulcerative colitis could legally be prescribed for any purpose a physician deemed appropriate
Together, these findings indicate that exon 10 is an important domain to maintain G6PD structural integrity and functionality, and mutations in this region of the enzyme commonly result in the most severe form of deficiency
Maintaining healthy antioxidant status supports overall cellular wellness and helps protect tissues from oxidative stress
Comment: A few commenters supported our proposal to require that the lookback period for the median allowed amount, the 10th and 90th percentile allowed amounts, and count of allowed amounts be no longer than 12 months prior to posting the MRF
