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2.1 Oxidation The process of oxidation is catalysed by a class of enzymes that are collectively called cytochrome P450 (Cyp-450)

SCFAs activate GPCRs (GPR43/41) and inhibit histone deacetylases (HDAC), promoting regulatory T-cell (Treg) differentiation while suppressing Th17 cell polarization within the joint, thereby restoring immune homeostasis and reducing pro-inflammatory cytokine release

of the Department of Pharmacology, Therapeutics and Toxicology, College of Medicine, University of Lagos, Nigeria, is gratefully acknowledged

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Zhu, W., Zeneng Wang, Z., et al