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For instance, in a rodent model of toxin-induced chronic liver injury, MMP-2 deficient mice demonstrated an almost twofold increase in liver fibrosis compared to wild-type mice [100], due to an enhanced type I collagen mRNA expression

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The 6-month lifestyle program is typically waived under the CV pathway

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Transfection was performed according to the manufacturers protocol, using 1 g of each CRISPR construct and 0.5 g PE 7584 Hygro#20 plasmid