For a more in-depth discussion on cost ASM performance category scoring, see section III.C.2.d.(3)(g)
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Synonyms: N-hexanoic-Tyr-Ile-(6) aminohexanoic amide, N-(1-Oxohexyl)-L-tyrosyl-N-(6-amino-6-oxohexyl)-L-isoleucinamide
What a COA (Certificate of Analysis) Should Include Identity Confirmation Mass spectrometry confirming the 3,749.2 Da molecular weight (the full lipidated form, NOT the ~3,400 Da backbone) Amino acid sequence verification including the Lys-20 lipidation point Purity Testing HPLC purity look for 98%+ purity Chromatogram showing a single dominant peak with minimal truncated or unlipidated impurity peaks Contamination Testing Endotoxin levels (cagrilintide is injected subcutaneous) Residual solvent analysis (acetonitrile, TFA from SPMS cleavage) Heavy metals screening How to Verify a COA Is Legitimate Check the testing lab Janoshik Analytical, MZ Biolabs, and Colmaric Analyticals are the standard
[DOI] [PubMed] [Google Scholar] 17.Ronga M, Fagetti A, Canton G, Paiusco E, Surace MF, Cherubino P