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R.ChabosseauP.et al (2018)

This is howthe active ingredient in Wegovy helps people lose weight

With obesity, no one wants to accept medication as a chronic treatment

Experimental research found that supplementation with SeGSH-enriched probiotics exerted a better protective effect on carbon tetrachloride-induced liver fibrosis than that with Se, GSH, or probiotics individually, as it increased GSH-related antioxidant activity and upregulated the silent information regulator 1 signaling pathway, thus helping reduce hepatic oxidative stress and inflammation [35]

Particular attention is devoted to -cell heterogeneity and dysfunction, including reduced expression of INS, MAFA, and genes regulating insulin secretion, alongside activation of stress-associated programs (ATF4, DDIT3)