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Cell migration against the flow can be observed in high-density cultures [234]

GLP- 1's anti-apoptotic and proliferative effects are also mediated by the PI3 K/Akt axis through the transactivation of the epidermal growth factor receptor (EGFR), which is connected to GLP- 1 receptor through c-Src activation and the generation of endogenous EGF like ligands [59]

Given the positive role of the Wnt/-catenin signaling pathway in partial hepatectomy model, it was assumed that it might also contribute to liver regeneration in AILI, which was then confirmed in some previous studies [8], [11], [12], [110]

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