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Dipeptide cleavage is carried out by a catalytic triad (Ser630, Asp708, His740)

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However, since it can be assumed that noticeably more people will benefit, our data provide a good basis for further research and considerations, as they most likely represent a minimum of the estimated eligibility for GLP-1 RA therapy

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The freeze-thaw cycle is particularly destructive, as repeated freezing and thawing compounds the damage with each cycle