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Furthermore, these structural modifications drastically extend its half-life from 20 minutes to a staggering 20 to 30 hours
The study involved more than 3,500 older adults (average age, 71 years) enrolled in the COSMOS trial
10.1016/j.brainres.2009.05.025 63
However, we must interpret these findings with caution, explicitly acknowledging the significant heterogeneity in study design, patient cohorts, and choice of comparator agents that characterizes the current body of literature
Hydrocortisone and dexamethasone prevent TNF--triggered sloughing of the glycocalyx, thereby improving vascular endothelial function [21, 119, 120]
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