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To address the issue mentioned above, stimulus-responsive fluorescence imaging strategies that can activate signal light-up only in the presence of biomarkers or pathological environments can afford higher tumor-to-normal tissue ratios (T/N ratio) and real-time biological information, making the activatable modality a preferred choice for disease diagnosis and therapy evaluation [21], [22], [23], [24], [25]

EPL 104 , 38003 (2013)