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ITCs are electrophilic compounds that have been shown to activate phase II detoxification enzymes, including glutathione S -transferases (GSTs), in several organisms 24,25,26
[DOI] [PMC free article] [PubMed] [Google Scholar] 7
As glutathione has antioxidant properties, it can help repair and protect the body from oxidative stress while sleeping
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Glycosuria contributes directly to improved glycemic control, while increased distal sodium delivery restores normal tubuloglomerular feedback, thereby lowering intraglomerular pressure, which is a key mechanism in slowing DKD progression [25,27]
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