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Of note, thyroid hormone, which is a well-known activator of fatty acid oxidation and the carnitine shuttle ( 43 ), is reported to activate SLC25A45 transcription in the liver via the binding of thyroid hormone receptor to the thyroid response element (TRE) on the promoter region of the SLC25A45 gene ( 43 )

2024;3:e70

These observations render caution to any excitement about the use of GCGR antagonism in the therapy of diabetes GC Receptor Mutations A locus corresponding to the GCGR has been identified in genomic scans for T2DM

The paraffin-embedded samples were then transected into 4-m-thick sections

Molecular Weight: 1815.08 g/mol