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4.4 Systemic sclerosis As a consequence of dysfunctional differentiation of fibroblasts to myofibroblasts and excessive deposition of extracellular matrix, systemic sclerosis (SSC) is a rare fibrotic autoimmune disease that leads to skin fibrosis (83)

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We encounter synthetic compounds in air fresheners, building materials, personal care products, and cleaning supplies that didn't exist generations ago

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