At the same time, withholding GLP-1RAs in the perioperative period is not without risk, as it may lead to suboptimal glycaemic control and loss of the cardiometabolic benefits associated with continued therapy [28, 42]
Fatigue Fatigue is reported by some patients, particularly in the early weeks
Before starting both semaglutide and Botox, make sure to discuss your full medical history with your doctor
Storck EM, zbalci C, Eggert US
Last reviewed: May 28, 2026 Last updated: May 28, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations